Your Epigenetics Tells a Better Story
Epigenetics is the study of biological mechanisms that can activate or inactivate your genes, which affects how cells read them and in turn produce functional products such as proteins. The SKINTELLI test measures DNA methylation, a well-characterized epigenetic mechanism, of genes strongly correlated to skin quality factors and ultimately cosmetic properties.
The Environment's Role
The degree of active or inactive states of your genes is dynamic and can be impacted by your skin’s exposure to the environment including the sun and, especially, the ingredients contained in skincare products. Epigenetic changes are naturally occurring as you age, but are also potentially reversible through proper environment stimuli.
Real Science For Your Skin
We use our proprietary STEM-seq method (skin-targeted epigenetic marker sequencing), which combines next-generation DNA sequencing and bisulfite-based DNA methylation detection, to bring you results that you can count on.
Other DNA tests use genotyping, which only looks at static genetic variants that don’t change since birth. Because skin is dynamic, we test for the epigenetic states of 40 genes that represent your current, not predisposed, skin quality.Buy Now
How SKINTELLI Compares
- Tested indirectly from saliva
Epigenetic Profilingwith SKINTELLI
- Tested directly from skin
- No scientific test
SKINTELLI is a direct-to-consumer personal epigenetic test developed by New York-based biotechnology company EpigenCare Inc. The purpose of the test is to discover the best matched skincare products on the market for the current quality of your skin. Through next-generation sequencing of your DNA, we assess the cosmetic appearance of your skin at the epigenetic level. Current buying decisions for skincare products are based on glamorous, mass marketing and sales consultants, which is far too general. This leads to you receiving the same blanket recommendations for taking care of your skin as everyone else. Even dermatologists typically only make skincare product recommendations based on what can be visually detected on a superficial basis. With SKINTELLI, you will gain not only insight into the current quality of your skin but also be matched with existing products on the market, ranging from brand name to indie boutique, based on the best-suited combination of ingredient compositions.
You will gain three types of insights:
- A profile snapshot that quantifies eight major skin quality factors in a 1-100 normalized score format. This score represents how active your genes are, with 100 being fully activated and 1 equivalent to complete inactivation. This calculation is based on an epigenetic mechanism known as DNA methylation, which controls gene activity.
- An in-depth explanation of what each of the eight skin quality factor means, and which skincare product ingredients can help to improve each factor. This general guidance offers you flexibility in making your own shopping decisions for brands.
- Products that are algorithmically matched to your skin profile based on the most optimal ingredient compositions that can optimally address all quality factors as a whole. You will receive 36 matches, ranging from brand name to indie boutique, which are separated into three price tiers.
SKINTELLI does not offer medical, diagnostic, or health condition assessments and is strictly for cosmetic applications. For health concerns about your skin, seek the advice of a dermatologist or physician.
When you purchase the SKINTELLI test, we will ship a sample collection kit to your designated address. The kit contains mildly sticky adhesives that you adhere to your forehead area and the corners of your eye to collect skin samples. The procedure takes less than 2 minutes and is painless. You will then place the adhesives in collection tubes and ship it back to us in the prepaid postage box. Once we receive your samples, we collect your DNA out of the adhesives and will prepare them for epigenetic-based sequencing. Once the test is complete, we discard your DNA and any remaining samples in less than 10 business days.
If you would like to see progress of your skin quality or regimen, SKINTELLI is a repeatable test. Your lifestyle and products used may affect the speed of which epigenetic changes occur such that they can be sufficiently detected by SKINTELLI. To account for this as well as any statistical deviations, we generally recommend one test every 6 months, although this may differ between users.
If you placed a pre-order for a SKINTELLI or an EpigenCare test prior to February 11, 2019, you will receive your sample collection kit in late February to early March. If you placed a qualifying order during the limited beta release, you will receive the kit within 3-7 business days. Any new pre-orders placed during the limited beta release will be shipped on a rolling basis through approximately June 2019. All reports are delivered 6-12 weeks from the time your collected samples are received by us.
You’ll be able to view your personalized report online 6-12 weeks after we receive your collected skin sample. We expect this turnaround period to be significantly reduced in the future. During the beta stages, testing may be somewhat slower than our intended regular schedule.
SKINTELLI is currently available in the USA in all states except New York and Maryland. The test may be made available to NY and MD residents as well as worldwide in the near future.
Yes. Test results will not be sent to the individual who ordered a SKINTELLI test, but rather to whoever registers a sample collection kit in his or her possession. Thus, you may gift an unregistered collection kit to someone else.
Any unopen and unregistered SKINTELLI sample collection kits may be returned for a refund within 30 days. All returns are subject to a $25 processing fee. Once the collection kit has been open, we regrettably can no longer issue a refund. If the kit has been open but is unused and unregistered, we suggest gifting the kit to someone else. Please report any damaged or incomplete kits immediately upon receipt or within 14 days in order to qualify for a replacement. If you purchased a SKINTELLI test but have not carried out the test yet, replacement kits (for sample collection only) can be purchased for $25. If we receive your sample and are unable to obtain sufficient DNA, we will notify you to re-do the collection process up to one time at no additional cost. Additional attempts may be subject to re-collection and handling fees.